L20F (p.Leu20Phe) variant of NFKB2 (Q00653)
L20F (p.Leu20Phe) in NFKB2 (Q00653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
L20F (p.Leu20Phe) variant details
- p.Leu20Phe
- gnomAD rs1297472674
- Missense
- Variant Prioritization Score for Impact Estimate 0.242
- CADD 7.25
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available