I24T (p.Ile24Thr) variant of NFKB2 (Q00653)
I24T (p.Ile24Thr) in NFKB2 (Q00653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
I24T (p.Ile24Thr) variant details
- p.Ile24Thr
- gnomAD 10-102396302-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.332
- MetaLR 0.07
- MetaSVM -1.04
- CADD 20.70
- PolyPhen-2 0.00
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available