I24F (p.Ile24Phe) variant of NFKB2 (Q00653)
I24F (p.Ile24Phe) in NFKB2 (Q00653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
I24F (p.Ile24Phe) variant details
- p.Ile24Phe
- gnomAD 10-102396301-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.259
- MetaLR 0.05
- MetaSVM -1.07
- CADD 18.70
- PolyPhen-2 0.08
- SIFT 0.16
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available