C57W (p.Cys57Trp) variant of NFKB2 (Q00653)
C57W (p.Cys57Trp) in NFKB2 (Q00653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
C57W (p.Cys57Trp) variant details
- p.Cys57Trp
- cosmic curated COSV51874
- ExAC rs779223172
- gnomAD rs779223172
- Missense
- Variant Prioritization Score for Impact Estimate 0.545
- CADD 24.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 7.5e-05)
- Structural context available