Y89F (p.Tyr89Phe) variant of NFKB1 (P19838)
Y89F (p.Tyr89Phe) in NFKB1 (P19838) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
Y89F (p.Tyr89Phe) variant details
- p.Tyr89Phe
- rs764399130
- gnomAD 4-102566997-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.494
- REVEL 0.45
- AlphaMissense 0.44
- MetaLR 0.30
- MetaSVM -0.43
- CADD 23.70
- PolyPhen-2 0.04
- Most common in the Ashkenazi Jewish population (allele frequency 3.8e-05)
- Structural context available
- Literature evidence available