S74T (p.Ser74Thr) variant of NFKB1 (P19838)
S74T (p.Ser74Thr) in NFKB1 (P19838) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
S74T (p.Ser74Thr) variant details
- p.Ser74Thr
- rs1304282431
- gnomAD 4-102537918-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.363
- REVEL 0.20
- CADD 23.30
- PolyPhen-2 0.10
- SIFT 0.04
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available
- Literature evidence available