L21F (p.Leu21Phe) variant of NFKB1 (P19838)
L21F (p.Leu21Phe) in NFKB1 (P19838) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
L21F (p.Leu21Phe) variant details
- p.Leu21Phe
- gnomAD 4-102529859-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.136
- REVEL 0.03
- CADD 17.40
- PolyPhen-2 0.20
- SIFT 0.11
- Population evidence available
- Structural context available
- Literature evidence available