H66W (p.His66Trp) variant of NFKB1 (P19838)
H66W (p.His66Trp) in NFKB1 (P19838) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
H66W (p.His66Trp) variant details
- p.His66Trp
- gnomAD 4-102537896-CCA-C
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.273
- CADD 27.20
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available