G68S (p.Gly68Ser) variant of NFKB1 (P19838)
G68S (p.Gly68Ser) in NFKB1 (P19838) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data, published literature, and structural context.
G68S (p.Gly68Ser) variant details
- p.Gly68Ser
- rs2149127915
- gnomAD 4-102537900-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.778
- REVEL 0.80
- AlphaMissense 1.00
- MetaLR 0.58
- MetaSVM 0.35
- CADD 29.70
- PolyPhen-2 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available