C87R (p.Cys87Arg) variant of NFKB1 (P19838)
C87R (p.Cys87Arg) in NFKB1 (P19838) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
C87R (p.Cys87Arg) variant details
- p.Cys87Arg
- rs1560679373
- gnomAD 4-102566990-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.399
- REVEL 0.26
- CADD 22.90
- PolyPhen-2 0.13
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available
- Literature evidence available