R25K (p.Arg25Lys) variant of NFE2L2 (Q16236)
R25K (p.Arg25Lys) in NFE2L2 (Q16236) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data.
R25K (p.Arg25Lys) variant details
- p.Arg25Lys
- Ensembl rs1558981030
- Missense
- Variant Prioritization Score for Impact Estimate 0.275
- REVEL 0.14
- CADD 19.80
- PolyPhen-2 0.10
- SIFT 0.31
- Most common in the African/African-American population (allele frequency 3e-05)