R25R (p.Arg25Arg) variant of NF2 (Merlin)
R25R (p.Arg25Arg) in NF2 (Merlin) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
R25R (p.Arg25Arg) variant details
- p.Arg25Arg
- gnomAD 22-29604073-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.513
- CADD 15.70
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available