Y10Y (p.Tyr10Tyr) variant of NEDD4L (E3 ubiquitin-protein ligase NEDD4-like)
Y10Y (p.Tyr10Tyr) in NEDD4L (E3 ubiquitin-protein ligase NEDD4-like) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
Y10Y (p.Tyr10Tyr) variant details
- p.Tyr10Tyr
- rs1449704902
- gnomAD 18-58044690-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.48
- CADD 11.00
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available
- NEDD4L WW domain domainome 1.0: score -0.623
- Literature evidence available