V9I (p.Val9Ile) variant of NEDD4L (E3 ubiquitin-protein ligase NEDD4-like)
V9I (p.Val9Ile) in NEDD4L (E3 ubiquitin-protein ligase NEDD4-like) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes experimental measurements and structural context.
V9I (p.Val9Ile) variant details
- p.Val9Ile
- TOPMed rs1209753272
- Missense
- Variant Prioritization Score for Impact Estimate 0.113
- REVEL 0.03
- ESM-1b 0.00
- AlphaMissense 0.08
- MetaLR 0.03
- MetaSVM -1.04
- SIFT 1.00
- Structural context available
- NEDD4L WW domain domainome 1.0: score -0.347