V82I (p.Val82Ile) variant of NEDD4L (E3 ubiquitin-protein ligase NEDD4-like)
V82I (p.Val82Ile) in NEDD4L (E3 ubiquitin-protein ligase NEDD4-like) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
V82I (p.Val82Ile) variant details
- p.Val82Ile
- ExAC rs762094975
- gnomAD rs762094975
- Missense
- Variant Prioritization Score for Impact Estimate 0.496
- REVEL 0.33
- ESM-1b 0.22
- AlphaMissense 0.39
- MetaLR 0.44
- MetaSVM -0.31
- CADD 32.00
- Most common in the HGDP:YORUBA population (allele frequency 0.024)
- Structural context available