S19S (p.Ser19Ser) variant of NEDD4L (E3 ubiquitin-protein ligase NEDD4-like)
S19S (p.Ser19Ser) in NEDD4L (E3 ubiquitin-protein ligase NEDD4-like) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S19S (p.Ser19Ser) variant details
- p.Ser19Ser
- rs1256086921
- gnomAD 18-58045080-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.26
- CADD 16.30
- Most common in the HGDP:BRAHUI population (allele frequency 0.065)
- Structural context available
- NEDD4L WW domain domainome 1.0: score -0.595
- Literature evidence available