L5L (p.Leu5Leu) variant of NEDD4L (E3 ubiquitin-protein ligase NEDD4-like)
L5L (p.Leu5Leu) in NEDD4L (E3 ubiquitin-protein ligase NEDD4-like) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
L5L (p.Leu5Leu) variant details
- p.Leu5Leu
- rs2081489841
- gnomAD 18-58044675-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.15
- CADD 9.84
- Most common in the HGDP:BERGAMOITALIAN population (allele frequency 0.045)
- Structural context available
- NEDD4L WW domain domainome 1.0: score -0.259
- Literature evidence available