F94L (p.Phe94Leu) variant of NEDD4L (E3 ubiquitin-protein ligase NEDD4-like)
F94L (p.Phe94Leu) in NEDD4L (E3 ubiquitin-protein ligase NEDD4-like) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
F94L (p.Phe94Leu) variant details
- p.Phe94Leu
- gnomAD rs2048000562
- Missense
- Variant Prioritization Score for Impact Estimate 0.738
- REVEL 0.84
- ESM-1b 1.00
- AlphaMissense 1.00
- MetaLR 0.45
- MetaSVM -0.08
- CADD 28.80
- Most common in the 1KG:ACB population (allele frequency 0.038)
- Structural context available