E18K (p.Glu18Lys) variant of NEDD4L (E3 ubiquitin-protein ligase NEDD4-like)
E18K (p.Glu18Lys) in NEDD4L (E3 ubiquitin-protein ligase NEDD4-like) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes experimental measurements and structural context.
E18K (p.Glu18Lys) variant details
- p.Glu18Lys
- gnomAD rs1321972184
- Missense
- Variant Prioritization Score for Impact Estimate 0.681
- ESM-1b 1.00
- AlphaMissense 0.30
- Structural context available
- NEDD4L WW domain domainome 1.0: score -0.667