D53G (p.Asp53Gly) variant of NEDD4L (E3 ubiquitin-protein ligase NEDD4-like)
D53G (p.Asp53Gly) in NEDD4L (E3 ubiquitin-protein ligase NEDD4-like) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
D53G (p.Asp53Gly) variant details
- p.Asp53Gly
- TOPMed rs1380359617
- Missense
- Variant Prioritization Score for Impact Estimate 0.447
- REVEL 0.27
- ESM-1b 1.00
- AlphaMissense 0.22
- MetaLR 0.29
- MetaSVM -0.49
- CADD 24.00
- Population evidence available
- Structural context available