D15D (p.Asp15Asp) variant of NEDD4L (E3 ubiquitin-protein ligase NEDD4-like)
D15D (p.Asp15Asp) in NEDD4L (E3 ubiquitin-protein ligase NEDD4-like) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
D15D (p.Asp15Asp) variant details
- p.Asp15Asp
- gnomAD 18-58044705-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.191
- CADD 9.02
- Most common in the HGDP:PATHAN population (allele frequency 0.14)
- Structural context available
- NEDD4L WW domain domainome 1.0: score -0.53
- Literature evidence available