A59S (p.Ala59Ser) variant of NEDD4L (E3 ubiquitin-protein ligase NEDD4-like)
A59S (p.Ala59Ser) in NEDD4L (E3 ubiquitin-protein ligase NEDD4-like) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
A59S (p.Ala59Ser) variant details
- p.Ala59Ser
- Ensembl rs866161211
- Missense
- Variant Prioritization Score for Impact Estimate 0.299
- REVEL 0.08
- ESM-1b 0.00
- AlphaMissense 0.14
- MetaLR 0.04
- MetaSVM -1.06
- CADD 21.70
- Population evidence available
- Structural context available