Y41Y (p.Tyr41Tyr) variant of NCSTN (Nicastrin)
Y41Y (p.Tyr41Tyr) in NCSTN (Nicastrin) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
Y41Y (p.Tyr41Tyr) variant details
- p.Tyr41Tyr
- rs747798872
- gnomAD 1-160344759-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.298
- CADD 11.10
- Most common in the HGDP:DRUZE population (allele frequency 0.1)
- Structural context available
- Literature evidence available