S35W (p.Ser35Trp) variant of NCSTN (Nicastrin)
S35W (p.Ser35Trp) in NCSTN (Nicastrin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data, published literature, and structural context.
S35W (p.Ser35Trp) variant details
- p.Ser35Trp
- gnomAD 1-160343755-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0541
- REVEL 0.05
- CADD 1.90
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available