Q59Q (p.Gln59Gln) variant of NCSTN (Nicastrin)
Q59Q (p.Gln59Gln) in NCSTN (Nicastrin) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
Q59Q (p.Gln59Gln) variant details
- p.Gln59Gln
- rs764437174
- gnomAD 1-160343768-A-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.256
- CADD 9.55
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available
- Literature evidence available