F23I (p.Phe23Ile) variant of NCSTN (Nicastrin)
F23I (p.Phe23Ile) in NCSTN (Nicastrin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data, published literature, and structural context.
F23I (p.Phe23Ile) variant details
- p.Phe23Ile
- gnomAD 1-160343760-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.059
- REVEL 0.02
- CADD 8.40
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available