D11N (p.Asp11Asn) variant of NCSTN (Nicastrin)
D11N (p.Asp11Asn) in NCSTN (Nicastrin) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes structural context.
D11N (p.Asp11Asn) variant details
- p.Asp11Asn
- NCI-TCGA Cosmic COSV5409
- TOPMed rs1648210558
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.197
- REVEL 0.17
- ESM-1b 0.00
- AlphaMissense 0.10
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available