V3A (p.Val3Ala) variant of NCF4 (Neutrophil cytosol factor 4)
V3A (p.Val3Ala) in NCF4 (Neutrophil cytosol factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
V3A (p.Val3Ala) variant details
- p.Val3Ala
- gnomAD 22-36861179-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0902
- REVEL 0.01
- MetaLR 0.08
- MetaSVM -1.04
- CADD 10.50
- PolyPhen-2 0.02
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available
- Literature evidence available