V20D (p.Val20Asp) variant of NCF4 (Neutrophil cytosol factor 4)
V20D (p.Val20Asp) in NCF4 (Neutrophil cytosol factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
V20D (p.Val20Asp) variant details
- p.Val20Asp
- gnomAD rs1181316793
- Missense
- Variant Prioritization Score for Impact Estimate 0.447
- REVEL 0.37
- MetaLR 0.20
- MetaSVM -0.69
- CADD 24.50
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available