S11I (p.Ser11Ile) variant of NCF4 (Neutrophil cytosol factor 4)
S11I (p.Ser11Ile) in NCF4 (Neutrophil cytosol factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
S11I (p.Ser11Ile) variant details
- p.Ser11Ile
- gnomAD rs1425070713
- Missense
- Variant Prioritization Score for Impact Estimate 0.37
- REVEL 0.17
- MetaLR 0.11
- MetaSVM -1.00
- CADD 33.00
- PolyPhen-2 0.75
- SIFT 0.00
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available