R33K (p.Arg33Lys) variant of NCF4 (Neutrophil cytosol factor 4)
R33K (p.Arg33Lys) in NCF4 (Neutrophil cytosol factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
R33K (p.Arg33Lys) variant details
- p.Arg33Lys
- ExAC rs773949075
- Missense
- Variant Prioritization Score for Impact Estimate 0.177
- REVEL 0.07
- MetaLR 0.03
- MetaSVM -1.03
- CADD 21.30
- PolyPhen-2 0.01
- SIFT 1.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available