N25K (p.Asn25Lys) variant of NCF4 (Neutrophil cytosol factor 4)
N25K (p.Asn25Lys) in NCF4 (Neutrophil cytosol factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
N25K (p.Asn25Lys) variant details
- p.Asn25Lys
- gnomAD 22-36864087-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.284
- REVEL 0.12
- MetaLR 0.10
- MetaSVM -1.00
- CADD 22.10
- PolyPhen-2 0.89
- SIFT 0.11
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available
- Literature evidence available