L16F (p.Leu16Phe) variant of NCF4 (Neutrophil cytosol factor 4)
L16F (p.Leu16Phe) in NCF4 (Neutrophil cytosol factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
L16F (p.Leu16Phe) variant details
- p.Leu16Phe
- ExAC rs755356622
- TOPMed rs755356622
- gnomAD rs755356622
- Missense
- Variant Prioritization Score for Impact Estimate 0.33
- REVEL 0.07
- MetaLR 0.08
- MetaSVM -1.10
- CADD 23.90
- PolyPhen-2 0.24
- SIFT 0.00
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available