I29F (p.Ile29Phe) variant of NCF4 (Neutrophil cytosol factor 4)
I29F (p.Ile29Phe) in NCF4 (Neutrophil cytosol factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
I29F (p.Ile29Phe) variant details
- p.Ile29Phe
- gnomAD 22-36864097-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.271
- REVEL 0.23
- MetaLR 0.12
- MetaSVM -1.03
- CADD 23.50
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available
- Literature evidence available