I26V (p.Ile26Val) variant of NCF4 (Neutrophil cytosol factor 4)
I26V (p.Ile26Val) in NCF4 (Neutrophil cytosol factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
I26V (p.Ile26Val) variant details
- p.Ile26Val
- 1000Genomes rs541007080
- ExAC rs541007080
- gnomAD rs541007080
- Missense
- Variant Prioritization Score for Impact Estimate 0.296
- REVEL 0.16
- MetaLR 0.15
- MetaSVM -0.96
- CADD 21.70
- PolyPhen-2 0.54
- SIFT 0.32
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available