I26T (p.Ile26Thr) variant of NCF4 (Neutrophil cytosol factor 4)
I26T (p.Ile26Thr) in NCF4 (Neutrophil cytosol factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
I26T (p.Ile26Thr) variant details
- p.Ile26Thr
- gnomAD 22-36864089-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.465
- REVEL 0.47
- MetaLR 0.27
- MetaSVM -0.38
- CADD 23.40
- PolyPhen-2 0.62
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available
- Literature evidence available