H63Y (p.His63Tyr) variant of NCF4 (Neutrophil cytosol factor 4)
H63Y (p.His63Tyr) in NCF4 (Neutrophil cytosol factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
H63Y (p.His63Tyr) variant details
- p.His63Tyr
- Ensembl rs1939889963
- Missense
- Variant Prioritization Score for Impact Estimate 0.116
- REVEL 0.05
- MetaLR 0.03
- MetaSVM -0.98
- CADD 12.90
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available