H63R (p.His63Arg) variant of NCF4 (Neutrophil cytosol factor 4)
H63R (p.His63Arg) in NCF4 (Neutrophil cytosol factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
H63R (p.His63Arg) variant details
- p.His63Arg
- ExAC rs767668921
- gnomAD rs767668921
- Missense
- Variant Prioritization Score for Impact Estimate 0.316
- REVEL 0.15
- MetaLR 0.08
- MetaSVM -1.04
- CADD 23.40
- PolyPhen-2 0.09
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available