F39S (p.Phe39Ser) variant of NCF4 (Neutrophil cytosol factor 4)
F39S (p.Phe39Ser) in NCF4 (Neutrophil cytosol factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
F39S (p.Phe39Ser) variant details
- p.Phe39Ser
- gnomAD rs1341984523
- Missense
- Variant Prioritization Score for Impact Estimate 0.457
- REVEL 0.37
- MetaLR 0.17
- MetaSVM -0.80
- CADD 29.60
- PolyPhen-2 0.98
- SIFT 0.03
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available