F35S (p.Phe35Ser) variant of NCF4 (Neutrophil cytosol factor 4)
F35S (p.Phe35Ser) in NCF4 (Neutrophil cytosol factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
F35S (p.Phe35Ser) variant details
- p.Phe35Ser
- cosmic curated COSV50620
- ExAC rs764060580
- gnomAD rs764060580
- Missense
- Variant Prioritization Score for Impact Estimate 0.455
- REVEL 0.44
- MetaLR 0.25
- MetaSVM -0.50
- CADD 26.00
- PolyPhen-2 1.00
- SIFT 0.03
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available