F13S (p.Phe13Ser) variant of NCF4 (Neutrophil cytosol factor 4)
F13S (p.Phe13Ser) in NCF4 (Neutrophil cytosol factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
F13S (p.Phe13Ser) variant details
- p.Phe13Ser
- ExAC rs754276557
- gnomAD rs754276557
- Missense
- Variant Prioritization Score for Impact Estimate 0.382
- REVEL 0.31
- MetaLR 0.14
- MetaSVM -0.94
- CADD 25.60
- PolyPhen-2 0.91
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available