D19V (p.Asp19Val) variant of NCF4 (Neutrophil cytosol factor 4)
D19V (p.Asp19Val) in NCF4 (Neutrophil cytosol factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
D19V (p.Asp19Val) variant details
- p.Asp19Val
- gnomAD 22-36864068-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.458
- REVEL 0.40
- MetaLR 0.18
- MetaSVM -0.76
- CADD 25.30
- PolyPhen-2 0.90
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available
- Literature evidence available