A9T (p.Ala9Thr) variant of NCF4 (Neutrophil cytosol factor 4)
A9T (p.Ala9Thr) in NCF4 (Neutrophil cytosol factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
A9T (p.Ala9Thr) variant details
- p.Ala9Thr
- TOPMed rs995268797
- gnomAD rs995268797
- Missense
- Variant Prioritization Score for Impact Estimate 0.207
- REVEL 0.03
- MetaLR 0.04
- MetaSVM -1.06
- CADD 23.10
- PolyPhen-2 0.01
- SIFT 0.53
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available