A4S (p.Ala4Ser) variant of NCF4 (Neutrophil cytosol factor 4)
A4S (p.Ala4Ser) in NCF4 (Neutrophil cytosol factor 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
A4S (p.Ala4Ser) variant details
- p.Ala4Ser
- gnomAD 22-36861181-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.247
- REVEL 0.05
- MetaLR 0.05
- MetaSVM -1.04
- CADD 22.30
- PolyPhen-2 0.04
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available
- Literature evidence available