Q115P (p.Gln115Pro) variant of NCF2 (Neutrophil cytosol factor 2)
Q115P (p.Gln115Pro) in NCF2 (Neutrophil cytosol factor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
Q115P (p.Gln115Pro) variant details
- p.Gln115Pro
- cosmic curated COSV10970
- gnomAD rs1672854950
- Missense
- Variant Prioritization Score for Impact Estimate 0.215
- REVEL 0.15
- MetaLR 0.24
- MetaSVM -0.83
- CADD 16.50
- PolyPhen-2 0.00
- SIFT 0.16
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available