M79L (p.Met79Leu) variant of NCF2 (Neutrophil cytosol factor 2)
M79L (p.Met79Leu) in NCF2 (Neutrophil cytosol factor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
M79L (p.Met79Leu) variant details
- p.Met79Leu
- ExAC rs137854512
- TOPMed rs137854512
- gnomAD rs137854512
- Missense
- Variant Prioritization Score for Impact Estimate 0.259
- REVEL 0.10
- MetaLR 0.10
- MetaSVM -1.01
- CADD 22.40
- PolyPhen-2 0.01
- SIFT 0.57
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available