I99T (p.Ile99Thr) variant of NCF2 (Neutrophil cytosol factor 2)
I99T (p.Ile99Thr) in NCF2 (Neutrophil cytosol factor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
I99T (p.Ile99Thr) variant details
- p.Ile99Thr
- ExAC rs766146068
- Missense
- Variant Prioritization Score for Impact Estimate 0.321
- REVEL 0.07
- MetaLR 0.07
- MetaSVM -1.00
- CADD 14.50
- PolyPhen-2 0.00
- SIFT 0.76
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available