F116V (p.Phe116Val) variant of NCF2 (Neutrophil cytosol factor 2)
F116V (p.Phe116Val) in NCF2 (Neutrophil cytosol factor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
F116V (p.Phe116Val) variant details
- p.Phe116Val
- TOPMed rs1672854807
- Missense
- Variant Prioritization Score for Impact Estimate 0.603
- REVEL 0.63
- MetaLR 0.52
- MetaSVM -0.18
- CADD 25.00
- PolyPhen-2 0.45
- SIFT 0.50
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available