D108N (p.Asp108Asn) variant of NCF2 (Neutrophil cytosol factor 2)
D108N (p.Asp108Asn) in NCF2 (Neutrophil cytosol factor 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
D108N (p.Asp108Asn) variant details
- p.Asp108Asn
- gnomAD rs749367579
- Missense
- Variant Prioritization Score for Impact Estimate 0.578
- REVEL 0.47
- MetaLR 0.48
- MetaSVM 0.14
- CADD 25.90
- PolyPhen-2 0.89
- SIFT 0.05
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available