P67L (p.Pro67Leu) variant of NCF1 (Neutrophil cytosol factor 1)
P67L (p.Pro67Leu) in NCF1 (Neutrophil cytosol factor 1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
P67L (p.Pro67Leu) variant details
- p.Pro67Leu
- gnomAD rs1351691379
- Missense
- Variant Prioritization Score for Impact Estimate 0.205
- REVEL 0.09
- MetaLR 0.19
- MetaSVM -0.88
- CADD 18.20
- PolyPhen-2 0.01
- SIFT 0.22
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available